Central neurotransmitters and regulation of gastric acid secretion.

Central neurotransmitters and control of prolactin secretion

Despite extensive study during the last 10 years, several aspects of the neural control of prolactin secretion are still unelucidated. In mammals, the most important feature of this control is the existence of a predominant inhibitory regulation, as demonstrated by a number of older experiments involving hypothalamo-hypophyseal deconnexion, interruption of the portal circulation, ectopic grafts...

Central peptidergic control of gastric acid secretion.

INHIBITION OF ACID SECRETION Inhibitory of regulation of gastric acid secretion is a accomplished through central, vagal, gastric, intestinal, and colonic mechanisms [1] TYPES OF ULCER

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Nesfatin-1 Inhibits Gastric Acid Secretion via a Central Vagal

34 Nesfatin-1, a novel hypothalamic peptide, inhibits nocturnal feeding behavior and 35 gastrointestinal motility in rodents. The effects of nesfatin-1 on gastrointestinal secretory 36 function, including gastric acid production, have not been evaluated. Nesfatin-1 was injected 37 into the 4 intracerebral ventricle (4V) of chronically cannulated rats to identify a nesfatin dose 38 sufficient to...

Regulation of gastric acid secretion by PKB/Akt2.

Pharmacological inhibition of phosphoinositol 3 kinase (PI3K) and partial deficiency of phosphoinositide dependent kinase PDK1 have previously been shown to enhance basal gastric acid secretion. PI3K/PDK1 dependent signaling involves activation of protein kinase B/Akt, which may thus be similarly involved in the regulation of gastric acid secretion. To test that hypothesis, gastric acid secreti...